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Translational Vaccinology for Global Health

Translational Vaccinology for Global Health
25 -29 October 2016
Park Plaza Riverbank London, London, United Kingdom

The time required to launch new global health vaccines is too long and the late failure rate is unsustainably high. Key barriers include insufficient diversity and quality of preclinical concepts and candidates, immunobiological ignorance, and a lack of understanding of correlates or mechanisms of protection.

Root causes include siloed science and linear thinking; poor integration across the discovery/development/delivery ecosystem; and slow entry and limited throughput in early human proof of concept testing. This Keystone Symposia meeting aims to bring together those pioneering novel, creative solutions to these problems of global vaccine discovery and development across the academic/biotech/product development partner/pharma spectrum.

Session Topics: • Controlled Human Infection Models • Workshop 1: Correlates of Protection • Human Immune Profiling • Toward PK/PD in B Cell Vaccinology • Workshop 2: Human Immunophenotyping • T Cells • Novel Approaches to Antigen Identification and Immunogen Design • Adjuvants, Mucosal and Otherwise • Clinical Trial Readouts • Workshop 3: Antigen Identification, Adjuvants, Formulations and Novel Delivery Platforms • Accelerating Global Health Vaccine R&D

Scientific Organizers: Christopher L. Karp, Bill & Melinda Gates Foundation, USA Gagandeep Kang, Christian Medical College, India Rino Rappuoli, GlaxoSmithKline Vaccines, Italy

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

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