Ghent University

Contact Information

  • First name:
    Edwin
  • Last name:
    Claerebout
  • Degree:
    DVM, PhD
  • Function title:
    professor
  • Phone:
    09-2647393
  • Full Time
  • Anywhere
  • Type of organisation

  • Posted 8 years ago
  • Organisation Type:
  • Knowledge institute
  • Type of knowledge institute:
    university
  • Name of university:
    University of Ghent - Universiteit Gent

Organisation Information

Research institute / Department:
Virology, Parasitology & Immunology
Laboratory / Research group:
Parasitology
Street and number:
Salisburylaan 133
Postal code:
9820
City:
Merelbeke
Country:
Belgium
Website:
http://www.vetparasitology.ugent.be/
Phone:
09-2647400
(Organization) Email:
guide@UGent.be
Key activities - Multiple choice:
Fundamental research
Preclinical research
Other key activities:
teaching
Therapeutic / Diagnostic area:
Infectious diseases – animal
Other diagnostic area:
none
Research focus:
vaccine development against parasitic helminths in ruminants
Relevant research projects:
H2020- PARAGONE
Tags:
parasite, vaccine, cattle, nematodes
Number of projects:
1
Project 1:

To comply with a requirement for prime quality animal products farmed in a way that is minimally harmful to the environment, immunological control of parasite infections is the most rational way forward. The Laboratory of Parasitology at Ghent University has in recent years developed experimental vaccines against the gastrointestinal cattle parasites Ostertagia ostertagi and Cooperia oncophora, based on Activation-associated Secreted Proteins (ASPs) released by the adult parasites. Immunisation of cattle with these antigens raises an effective immune response, resulting in a significant reduction in numbers of worms and worm eggs shed, sufficient to protect calves against parasitic gastroenteritis during their first grazing season. Our current research is focused on the recombinant expression of the antigens and the analysis of the antigen structure and the protective immune responses induced by the vaccine.